![]() ![]() Deficiency and blockage of neurotrophic factors.Loss of motor neurons by genetic programs of microglial cells and astrocytes. ![]() It is known that two or more factors are involved in combination rather than a single factor that independently causes the disease. The following factors are known to be involved from case reports of patients. Sporadic factors Like other degenerative brain diseases, the cause of the disease is not clearly known.
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